Analyzing ChatGPT's Aptitude in an Introductory Computer Engineering Course

ChatGPT has recently gathered attention from the general public and academia as a tool that is able to generate plausible and human-sounding text answers to various questions. One potential use, or abuse, of ChatGPT is in answering various questions or even generating whole essays and research papers in an academic or classroom setting. While recent works have explored the use of ChatGPT in the context of humanities, business school, or medical school, this work explores how ChatGPT performs in the context of an introductory computer engineering course. This work assesses ChatGPT's aptitude in answering quizzes, homework, exam, and laboratory questions in an introductory-level computer engineering course. This work finds that ChatGPT can do well on questions asking about generic concepts. However, predictably, as a text-only tool, it cannot handle questions with diagrams or figures, nor can it generate diagrams and figures. Further, also clearly, the tool cannot do hands-on lab experiments, breadboard assembly, etc., but can generate plausible answers to some laboratory manual questions. One of the key observations presented in this work is that the ChatGPT tool could not be used to pass all components of the course. Nevertheless, it does well on quizzes and short-answer questions. On the other hand, plausible, human-sounding answers could confuse students when generating incorrect but still plausible answers.Comment: 6 page

Bioanalytical Method Development and Validation: A Review

For various types of drug approval processes like INDs, NDAs, ANDAs, veterinary drug approval, the data related to bioanalytical method development and validation is needed to sponsors. Various agencies namely US FDA, American association of pharmaceutical scientists (AAPS), Health protection Branch (HPB), Association of analytical chemists (AOAC), Center for Veterinary Medicine (CVM), U.S. Department of Health and Human Services Food and drug Administration, Center for Drug Evaluation and Research (CDER), European Medicine Agency (EMA), China Food and Drug administration(CFDA), European Bioanalytical Forum (EBF), Global CRO council (GCC), ANVISA (Brazil), Japan Bioanalytical Forum (JBF) had done collective efforts at different timings to regulate and harmonize bioanalytical method development and validation

Hardware Architecture for a Quantum Computer Trusted Execution Environment

The cloud-based environments in which today's and future quantum computers will operate, raise concerns about the security and privacy of user's intellectual property. Quantum circuits submitted to cloud-based quantum computer providers represent sensitive or proprietary algorithms developed by users that need protection. Further, input data is hard-coded into the circuits, and leakage of the circuits can expose users' data. To help protect users' circuits and data from possibly malicious quantum computer cloud providers, this work presented the first hardware architecture for a trusted execution environment for quantum computers. To protect the user's circuits and data, the quantum computer control pulses are obfuscated with decoy control pulses. While digital data can be encrypted, analog control pulses cannot and this paper proposed the novel decoy pulse approach to obfuscate the analog control pulses. The proposed decoy pulses can easily be added to the software by users. Meanwhile, the hardware components of the architecture proposed in this paper take care of eliminating, i.e. attenuating, the decoy pulses inside the superconducting quantum computer's dilution refrigerator before they reach the qubits. The hardware architecture also contains tamper-resistant features to protect the trusted hardware and users' information. The work leverages a new metric of variational distance to analyze the impact and scalability of hardware protection. The variational distance of the circuits protected with our scheme, compared to unprotected circuits, is in the range of only $0.16$ to $0.26$. This work demonstrates that protection from possibly malicious cloud providers is feasible and all the hardware components needed for the proposed architecture are available today

An unusual presentation of nabothian cyst: a case report

Nabothian cysts are common gynecologic findings and rarely of clinical significance. They are not problematic unless they are sizeable and present secondary symptoms like in this case. Nabothian cysts are usually associated with chronic cervicitis, an inflammatory condition of cervix, and are harmless and usually disappear on their own. Here we report an interesting case of multiple large nabothian cysts presented with continuous, thin & copious watery discharge, a distressing symptom, mimicking genitourinary fistula. This case is reported for the rarity of symptoms of continuous copious thin watery discharge per vaginum. Very rarely nabothian cyst needs hysterectomy as in our case

Implementation of ASK, PSK and FSK on FPGA

ABSTRACT This paper present the review on an implementation of ASK, PSK and FSK modulators and demodulators on FPGA using Quartus II software. The ASK,PSK and FSK modulators and demodulators system is simulated using MATLAB/SIMULINK environment ,DSP Builder and Quartus II. The DSP builder Signal Compiler block reads Simulink Model Files (.mdl) and writes out VHDL files and Tcl scripts for hardware implementation and simulation. Quartus II, a tool from altera used to implement the design on two Cyclone II Starter kit board. The first board behaves as a modulator and second as a demodulator. The modulated signal was achieved in the first Cyclone II board, passed through a channel and transmitted to the second board, which behaves as a demodulator. At the end of the demodulator, the modulating signal was obtained

STAR (Survey for ManagemenT of DiAbetes with FibeR-rich Nutrition Drink): A Pan India Survey to Understand the Physician and Patient Perspective Regarding the Role of Dietary Fiber Supplement in the Management of Type 2 Diabetes

Objectives: The aim of the STAR survey was to understand the physicians’ knowledge, attitude and perception regarding the role of nutritional dietary fiber supplements in the daily management of type 2 diabetes mellitus (T2DM). It also aimed to compare the changes in glycemic parameters as well as energy and satiety levels between patients taking a high-fiber supplement and those not taking a fiber supplement. Methods: Two cross-sectional pan-India surveys were conducted. The first was among 152 physicians who had >5 years of experience in treating patients with T2DM and treated >50 patients with T2DM per month. A self-administered paper-based questionnaire was used for the survey. The other survey was conducted among 3,042 patients with T2DM who were receiving treatment with antidiabetics. These patients were further categorized into the Horlicks Diabetes Plus (HDP) group, which consisted of 1,524 patients who had consumed the HDP fiber supplement for a minimum of 3 months and the non-HDP group, which included 1,518 patients who had never consumed HDP. Results: Almost all physicians prescribed fiber-rich nutritional supplements to their patients with T2DM and believed that dietary fiber has an important role in managing glycated hemoglobin (HbA1c) values, healthy weight and cholesterol levels. Among the main benefits of HDP seen by physicians were improvement in satiety levels and increase in physical activity, reduction in HbA1c, fasting and postprandial glucose, and reduction in dose and/or number of hypoglycemic medications. All physicians recommended that it was important to increase awareness among patients as well as doctors regarding the benefits of HDP in patients with T2DM. Patients in the HDP group reported a mean decrease of 0.72 in their HbA1c value which was statistically significant at 3 months (8.04 at baseline to 7.32 at 3 months). In contrast, the non-HDP group showed a non-statistically significant decrease of 0.61 in HbA1c from a baseline value of 8.15. Furthermore, patients reported a significant decrease in weight of 3 kg in 3 months from baseline value of 72.11 kg to 69.11 kg. This reduction in weight was observed in 82% patients in the HDP group, while the non-HDP group showed an insignificant weight reduction from a baseline value of 72.14 kg to 71.46 kg in 3 months. About 83% of patients reported feeling full for longer periods of time and 92.62% reported feeling more energetic after starting HDP. The compliance and satisfaction rates with HDP were 96% and 75%, respectively. Conclusion: A high-fiber supplement taken along with patients’ existing antidiabetic treatment plan has the potential to decrease glycemic parameters and weight while increase the satiety and energy levels among patients with T2DM. However, these results need to be evaluated further with long-term clinical studies conducted in the real world.&nbsp

Fast and Efficient Hardware Implementation of HQC

This work presents a hardware design for constant-time implementation of the HQC (Hamming Quasi-Cyclic) code-based key encapsulation mechanism. HQC has been selected for the fourth round of NIST\u27s Post-Quantum Cryptography standardization process and this work presents the first, hand-optimized design of HQC key generation, encapsulation, and decapsulation written in Verilog targeting implementation on FPGAs. The three modules further share a common SHAKE256 hash module to reduce area overhead. All the hardware modules are parametrizable at compile time so that designs for the different security levels can be easily generated. The design currently outperforms the other hardware designs for HQC, and many of the fourth-round Post-Quantum Cryptography standardization process, with one of the best time-area products as well. For the combined HighSpeed design targeting the lowest security level, we show that the HQC design can perform key generation in 0.09ms, encapsulation in 0.13ms, and decapsulation in 0.21ms when synthesized for an Xilinx Artix 7 FPGA. Our work shows that when hardware performance is compared, HQC can be a competitive alternative candidate from the fourth round of the NIST PQC competition

Maternal antecedents of adiposity and studying the transgenerational role of hyperglycemia and insulin (MAASTHI): a prospective cohort study : Protocol of birth cohort at Bangalore, India.

BACKGROUND: India is experiencing an epidemic of obesity-hyperglycaemia, which coincides with child bearing age for women. The epidemic can be sustained and augmented through transgenerational transmission of adiposity and glucose intolerance in women. This presents an opportunity for exploring a clear strategy for the control of this epidemic in India. We conducted a study between November 2013 and May 2015 to inform the design of a large pregnancy cohort study. Based on the findings of this pilot, we developed the protocol for the proposed birth cohort of 5000 women, the recruitment for which will start in April 2016. The protocol of the study documents the processes which aim at advancing the available knowledge, linking several steps in the evolution of obesity led hyperglycemia. METHODS: Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI) is a cohort study in the public health facilities in Bangalore, India. The objective of MAASTHI is to prospectively assess the effects of glucose levels in pregnancy on the risk of adverse infant outcomes, especially in predicting the possible risk markers of later chronic diseases. The primary objective of the proposed study is to investigate the effect of glucose levels in pregnancy on skinfold thickness (adiposity) in infancy as a marker of future obesity and diabetes in offspring. The secondary objective is to assess the association between psychosocial environment of mothers and adverse neonatal outcomes including adiposity. The study aims to recruit 5000 pregnant women and follow them and their offspring for a period of 4 years. The institutional review board at The Indian Institute of Public Health (IIPH)-H, Bangalore, Public Health Foundation of India has approved the protocol. All participants are required to provide written informed consent. DISCUSSION: The findings from this study may help to address important questions on screening and management of high blood sugar in pregnancy. It may provide critical information on the specific determinants driving the underweight-obesity-T2DM epidemic in India. The study can inform the policy regarding the potential impact of screening and management protocols in public healthcare facilities. The public health implications include prioritising issues of maternal glycemic control and weight management and better understanding of the lifecourse determinants in the development of T2DM

Demonstration of a Longitudinal Action Medical Mission (LAMM) Model to Teach Point-of-Care Ultrasound in Resource-Limited Settings

BACKGROUND: Short-term medical missions prevail as the most common form of international medical volunteerism, but they are ill-suited for medical education and training local providers in resource-limited settings. OBJECTIVE: The purpose of this study is to evaluate the effectiveness of a longitudinal educational program in training clinicians how to perform point-of-care ultrasound (POCUS) in resource-limited clinics. DESIGN: A retrospective study of such a four-month POCUS training program was conducted with clinicians from a rural hospital in Haiti. The model included one-on-one, in-person POCUS teaching sessions by volunteer instructors from the United States and Europe. The Haitian trainees were assessed at the start of the program and at its conclusion by a direct objective structured clinical examination (OSCE), administered by the visiting instructors, with similar pre- and post- program ultrasound competency assessments. RESULTS: Post-intervention, a significant improvement was observed (p < 0.0001), and each trainee showed significant overall improvement in POCUS competency independent of the initial competency pre-training (p < 0.005). There was a statistically significant improvement in POCUS application for five of the six medically relevant assessment categories tested. CONCLUSION: Our results provide a proof-of-concept for the longitudinal education-centered healthcare delivery framework in a resource-limited setting. Our longitudinal model provides local healthcare providers the skills to detect and diagnose significant pathologies, thereby reducing avoidable morbidity and mortality at little or no addition cost or risk to the patient. Furthermore, training local physicians obviates the need for frequent volunteering trips, saving costs in healthcare training and delivery